The silkworm holds a treasure beyond the luxury of exquisite
textiles. It's called serrapeptase (AKA Serratio Peptidase or SP,
DanzenTM, AniflazymTM SerraZymeTM), a powerful protolytic enzyme that
dissolves all nonliving tissue, including blood clots, cysts,
arterial plaque and inflammation in all forms.
The mighty enzyme offers a viable alternative to salicylates (such as
aspirin), ibuprofen, and NSAIDS as well as steroidsa boon for those
suffering with rheumatoid arthritis and a wide array of other
autoimmune diseases that affect the inflammatory response, including
ulcerative colitis, psoriasis, uveitis, allergies, and some forms of
cancer.
While steroidal and nonsteroidal antiinflammatory drugs may offer
temporary, symptomatic relief from pain, swelling and inflammation,
they may also be immunosuppressive and known to hold dangerous side
effects. Serrapeptase, on the other hand, eases pain and swelling
with no inhibitory effects on prostaglandins and no gastrointestinal
side effects. The immunologically active enzyme is completely bound
to the alpha 2 macroglobulin in biological fluids.
The physiologic agent is isolated from the microorganism Serratia
E15, an enzyme naturally present in the silkworm intestine which
allows the emerging moth to dissolve its cocoon. Clinical use of
serrazyme as an antiinflammatory in Europe and Asia spans over twenty
five years. Treatment includes chronic sinusitis, elimination of
bronchopulmonary secretions (the enzyme breaks down protein fibers,
allowing mucous to thin), sprains and torn ligaments, and other
traumatic injuries, idiopathic edema, as well as postoperative
inflammation.
Studying postoperative swelling and pain reduction of the upper ankle
joint, a test was carried out in 3 randomized groups of 66 patients,
each with fresh rupture of the lateral ligament treated surgically
between December 1986 and April 1987. The group receiving SP saw a
50% decrease in swelling on the third postoperative day. Decreased
pain, for the most part, correlated with reduction in swelling. The
SP group became rapidly pain-free. The two control groups, using
traditional elevation of the leg, bed rest, with and without
applications of ice, had no reduction in swelling at that time. (Esch
PM, Gerngross H, Fabian A, Fortachr Med,107(4):67.8, 71-2 1989 Feb 10)
Another multi-centre, double-blind, placebo-controlled trial was
carried out to investigate the clinical efficacy of SP in 174
patients who underwent Caldwell-Luc antrotomy for chronic empyema.
Eighty-eight patients received 10 mg SP 3 times the day before
surgery, once the night of the operation and 3 times daily for 5 days
after surgery; the other 86 received a placebo. The degree of
swelling in the serrapeptase-treated patients was significantly less
than that in the placebo-treated patients at every point of
observation after surgery up to the 5th day. Maximal buccal swelling
throughout all the postoperative points of observation was also
significantly smaller in size in the SP group. No side effects were
reported. (Tachibana M, Mizukosi 0, Harada Y, Kawamoto K, Nakai Y.
Source: Pharmathera-peutica, 3(8):526-30 1984).
Additionally, SP in a 70 patient, double-blind controlled trial
treating breast engorgement saw SP improve breast pain and swelling
in significant numbers of the treatment group with no adverse
reactions. (Kee WH, Tan SL; Lee V, Salmon YM .Singapore Med J, 30
(I) :48-54 1989 Feb)
Researchers in Germany have used SP to treat atherosclerosis since
serrapeptase helps to digest atherosclerotic plaque without harming
healthy cells lining the arterial wall. The hardened, narrow arterial
wall is considered the cumulative result of microscopic trauma with
inflammation occurring in the presence of oxidized lipids
serrapeptase works on both inflammation as well as dissolving the
avital plaque. Unlike cholesterol-blocking drugs, serapeptase clears
the avital tissue from the arterial wall without interfering with
cholesterol synthesis. In fact, when taking serrapeptase, cholesterol
levels may rise as it is dissolved from the arteries to be eliminated
from the body (cholesterol in its pure state is an antioxidant and a
necessary component of steroidal hormones and the major organ systems
in the body).
Medications blocking cholesterol biosynthesis hold the threat of
liver, eye, lung and other soft tissue damage. While studies with SP
in the treatment of coronary artery disease are relatively new; some
literature reports SP as being superior to, and faster than,
chelation.
The late German physician Dr. Hans Nieper used serrapeptase to treat
arterial blockage in his coronary patients, reporting that
serrapeptase also dissolves blood clots, and causes varicose veins to
shrink or diminish. Dr. Nieper told of a woman scheduled for hand
amputation and a man scheduled for bypass surgery; both recovered
quickly without surgery after treatment with serrapeptase.
In addition, widespread use has included fibrocystic breast disease
and carpal tunnel syndrome.
The enzyme is also used to facilitate the therapeutic effect of
antibiotics in the treatment of infection. In urology serrapeptase
has been successfully employed to treat cystitis and epididymitis.
Serrapeptase is available as SerraZyme in 10 mg enterically coated
tablets that are equivalent to 20,000 IU activity.
Recommended Usage: For inflammation is 1 tablets three times daily on
an empty stomach. For arterial blockage 1 tablets twice daily or as
directed by your health professional. (In acute conditions, your
health care professional may recommend that you take 2 tablets on an
empty stomach 6 times per day). Copyright, Julia Busch 2000